β-KETO ESTERS FROM REACTION OF ETHYL DIAZOACETATE WITH KETONES
نویسندگان
چکیده
منابع مشابه
β-Keto esters from ketones and ethyl chloroformate: a rapid, general, efficient synthesis of pyrazolones and their antimicrobial, in silico and in vitro cytotoxicity studies
BACKGROUND Pyrazolones are traditionally synthesized by the reaction of β-keto esters with hydrazine and its derivatives. There are methods to synthesize β-keto esters from esters and aldehydes, but these methods have main limitation in varying the substituents. Often, there are a number of methods such as acylation of enolates in which a chelating effect has been employed to lock the enolate a...
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Ethyl diazoacetate is a versatile compound in organic chemistry and frequently used on lab scale. Its highly explosive nature, however, severely limits its use in industrial processes. The in-line coupling of microreactor synthesis and separation technology enables the synthesis of this compound in an inherently safe manner, thereby making it available on demand in sufficient quantities. Ethyl ...
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ژورنال
عنوان ژورنال: Canadian Journal of Chemistry
سال: 1964
ISSN: 0008-4042,1480-3291
DOI: 10.1139/v64-205